Key Highlights
• Reporter gene assay kits are analytical tools used in molecular biology to study gene expression and cellular processes. These kits incorporate a reporter gene, such as luciferase or GFP, into a target organism's genome. When the gene of interest is activated, the reporter gene produces a detectable signal (light or fluorescence), allowing researchers to measure and quantify gene expression levels. This technique aids in understanding genetic regulation, drug screening, and signal pathway analysis. Reporter gene assay kits streamline experimentation, offering a high-throughput, non-invasive means to monitor gene activity and assess the effects of various treatments on cellular behavior.
• The market size of the worldwide Reporter Gene Assay Kits Industry surpassed USD XX billion in 2022, and by 2032, it is projected to reach USD XX billion, boosting at a CAGR of XX%.
• In April 2022, at the World CDx Summit in London, Illumina announced a long-term strategic agreement with Janssen Biotech to expedite the development of precision medicines. The cooperation intends to make use of Illumina's capabilities, which include AI-based genome interpretation tools, whole-genome sequencing, and multi-omic analysis services.
• The market is likely to be driven by an increase in demand for cell-based High-Throughput Screening (HTS) assays. Furthermore, the increased use of reporter genes in the investigation of signal transduction pathways emanating from cell surface receptors increases market growth. Reporter gene assays are one of the most widely used cell-based assays for elucidating the biological role of target molecules. As a result, researchers choose fluorescence assays for real-time analysis of dynamic events in living cells. This is due to the availability of different coloured reporter gene variations, as well as the fact that cell lysis or the addition of any form of substrate is not necessary for quantification. Furthermore, -galactosidase and Chloramphenicol Acyltransferase (CAT) are widely present in the HTS of pharmacological targets. A large increase in the number of research studies focusing on drug discovery and development is projected to drive product adoption and hence the market. Furthermore, reporter gene assays are often used in HTS techniques to identify chemical modulators that act on biological pathways. The difficulty that reporter genes encounter in discriminating between targeted drugs in biological pathways and the compounds in the assay protocol are expected to drive demand even higher.
Scope of the Industry Profile
Key Players
• QIAGEN (Germany)
• Thermo Fisher Scientific (US)
• Sartorius AG (Germany)
• Berthold Technologies GmbH & Co. KG (India)
• Promega Corp. (US)
• Marker Gene Technologies, Inc. (US)
• Merck KGaA (Germany)
• F. Hoffmann-La Roche AG (Switzerland)
• PerkinElmer Life Science (US)
• Bio-Rad Laboratories (US)
Segmentation
By Product
• Luciferase Assays
• Fluorescent Protein-related Assays
• Chloramphenicol Acetyltransferase Assays
• Secreted Alkaline
• Phosphatase Assays
• Beta-Galactosidase Assays
• Beta-Glucuronidase Assays
• Other Assays
By Application
• Cell Signalling Pathways
• Promoter Structural and Functional Analysis
• Protein Interaction
• Gene Regulation
By End User
• Hospital & Diagnostic Laboratories
• Academic & Research Institutes
• Contract Research Organizations (CROs)
• Pharmaceutical & Biotechnology Companies
What to Expect from Industry Profile
1. Save time carrying out entry-level research by identifying the size, growth, major segments, and leading players in the Reporter Gene Assay Kits market in the world.
2. Use the PORTER’s Five Forces analysis to determine the competitive intensity and therefore market attractiveness of the Global Reporter Gene Assay Kits market.
3. Leading company profiles reveal details of key Reporter Gene Assay Kits market players’ global operations, strategies, financial performance & their recent developments.
4. Add weight to presentations and pitches by understanding the future growth prospects of the Global Reporter Gene Assay Kits market with forecast for decade by both market share (%) & revenue (USD Million).
Recent Development
• In April 2022, at the World CDx Summit in London, Illumina announced a long-term strategic agreement with Janssen Biotech to expedite the development of precision medicines. The cooperation intends to make use of Illumina's capabilities, which include AI-based genome interpretation tools, whole-genome sequencing, and multi-omic analysis services.
• In February 2022, Tesis Biosciences, a leader in targeted genetic sequencing, bought Genome Explorations to enhance its focus on clinical research and commercial development.
Segment Insights
End-user
Cell-based assays are increasingly being used in pharmaceutical product assessment. This has been a major driver of the segment's growth. Furthermore, iLite technology is gaining favour among pharmaceutical businesses for pharma product testing. Because of the widespread use of reporter gene assays in clinical diagnostic applications, the end-use segment for hospitals and diagnostic laboratories is predicted to grow at the quickest rate. Several medical contexts are actively working toward the same goal and are currently doing research on the possibility of these tests in non-invasive diagnostic applications. In addition, a big number of hospitals are partnering with universities to conduct research activities that necessitate the usage of the product.
Application
In recent years, the number of high-throughput evaluation studies performed to determine the drug ability of specific compounds has expanded. Reporter genes are often used in such investigations, which should contribute to market expansion. Furthermore, reporter gene constructs have transformed protozoan parasite transfection research. This is due to the fact that these constructions aid in the investigation of cellular host-parasite interactions. This has aided in the development of drug screens for novel compounds and medications that work against parasites. Furthermore, because reporter assays provide a solid foundation for analysing disease development, they are increasingly being used in drug discovery initiatives. Because they can reproduce a complex living system, cell-based reporter gene assays are employed in the phenotypic screening of drug development candidates.
Regional Insights
North America is expected to dominate the global market because of technical advances in diagnostic and reporter gene assay products used for disease testing, the. Because of investments by biotechnology businesses and health care facilities to speed the development of gene treatments, the region will maintain its leading position during the anticipated years. The increasing investment by biotechnological and pharmaceutical businesses in creating facilities dedicated to gene therapy and associated genetic goods drives market expansion. Taysha Gene Therapies, Inc., for example, signed a lease agreement in December 2020 to occupy and configure a commercial-scale current Good Manufacturing Practices (cGMP) manufacturing facility in Durham, North Carolina for preclinical, clinical, and commercial production of its gene therapy pipeline. Pfizer Inc. also announced the inauguration of a new, cutting-edge clinical manufacturing facility in Durham, North Carolina, in December 2021. The facility expands Pfizer's end-to-end gene therapy capabilities and expands the company's current footprint in North Carolina.
1 INTRODUCTION
1.1 Study Objectives
1.2 Market Definitions
1.2.1 Inclusions & Exclusions
1.2.2 Region: Inclusions & Exclusions
1.2.3 Study Scope
1.2.3.1 Markets Covered
1.2.3.2 Regional Scope
1.2.3.3 Years Considered
1.2.4 Currency Considered
1.2.5 Limitations
1.2.6 Summary Of Report (Chapter Wise Summary)
2 RESEARCH METHODOLOGY
2.1 Research Data
2.1.1 Secondary & Primary Research
2.1.2 Secondary Data
2.1.2.1 Secondary Sources
2.1.3 Primary Data
2.1.3.1 Primary Sources
2.2 Market Breakdown & Data Triangulation
2.3 Market Size Estimation
2.3.1 Bottom-Up Approach
2.3.2 Top-Down Approach
2.4 Research Assumptions & Limitations
2.4.1 Assumptions
2.4.2 Limitations
3 EXECUTIVE SUMMARY
4 ACROSS THE GLOBE
4.1 Upcoming Attractive Market Opportunities
4.2 Country Wise Market Growth
4.3 Segment Wise Market Growth
5 MARKET OVERVIEW
5.1 Market Introduction
5.2 Market Dynamics
5.2.1 Drivers
5.2.2 Restraints
5.2.3 Opportunities
5.2.4 Challenges
5.3 PORTOR’S Five Forces Analysis
5.3.1 Threat of New Entrants
5.3.2 Threat of Substitutes
5.3.3 Bargaining Power of Suppliers
5.3.4 Bargaining Power of Buyers
5.3.5 Intensity of Competitive Rivalry
5.4 Market Premium insights (Enterprise license)
5.4.1 Case Study Analysis
5.4.2 Country Wise Import & Export Data (If
Applicable)
5.4.3 Regulatory Bodies & Authorization
Across the Globe
5.4.4 Key Conferences & Events: 2022 &
2023
5.4.5 Top Patents for The Market: 2022
6 REPORTER GENE ASSAY KITS MARKET
OVERVIEW, BY APPLICATION
6.1 Global Market Revenue & Share Analysis, By Application
6.1.1 Cell Signaling Pathways
6.1.2 Promoter Structural and Functional
Analysis
6.1.3 Protein Interaction
6.1.4 Gene Regulation
6.2 Global Market Revenue & Share Analysis, 2018 – 2022
6.3 Global Market Revenue & Share Forecast Analysis, 2023 –
2032
6.4 Key Takeaways
7 REPORTER GENE ASSAY KITS MARKET
OVERVIEW, BY END USER
7.1 Global Market Revenue & Share Analysis, By End User
7.1.1 Hospital & Diagnostic Laboratories
7.1.2 Academic & Research Institutes
7.1.3 Contract Research Organizations (CROs)
7.1.4 Pharmaceutical & Biotechnology
Companies
7.2 Global Market Revenue & Share Analysis, 2018 – 2022
7.3 Global Market Revenue & Share Forecast Analysis, 2023 –
2032
7.4 Key Takeaways
8 REPORTER GENE ASSAY
KITS MARKET OVERVIEW, BY PRODUCT
8.1 Global Market Revenue & Share Analysis, By Product
8.1.1 Luciferase Assays
8.1.2 Fluorescent Protein-related Assays
8.1.3 Chloramphenicol Acetyltransferase Assays
8.1.4 Secreted Alkaline
8.1.5 Phosphatase Assays
8.1.6 Beta-Galactosidase Assays
8.1.7 Beta-Glucuronidase Assays
8.1.8 Other Assays
8.2 Global Market Revenue & Share Analysis, 2018 – 2022
8.3 Global Market Revenue & Share Forecast Analysis, 2023 –
2032
8.4 Key Takeaways
9 REPORTER GENE ASSAY KITS MARKET
OVERVIEW, BY REGION
9.1 Global Market Revenue & Share Analysis, By Region
9.1.1 North America
9.1.2 Europe
9.1.3 Asia Pacific
9.1.4 Middle East & Africa
9.1.5 South America
9.2 Global Market Revenue & Share Analysis, 2018 – 2022
9.3 Global Market Revenue & Share Forecast Analysis, 2023 –
2032
9.4 Key Takeaways
10 NORTH AMERICA MARKET
ANALYSIS
10.1 North America Market Revenue & Share Analysis, By
Application
10.2 North America Market Revenue & Share Analysis, By End User
10.3 North America Market Revenue & Share Analysis, By Product
10.4 North America Market Revenue & Share Analysis, By Country
10.4.1 US
10.4.2 Canada
10.4.3 Mexico
10.5 Key Takeaways
11 EUROPE MARKET ANALYSIS
11.1 Europe Market Revenue & Share Analysis, By Application
11.2 Europe Market Revenue & Share Analysis, By End User
11.3 Europe Market Revenue & Share Analysis, By Product
11.4 Europe Market Revenue & Share Analysis, By Country
11.4.1 UK
11.4.2 Italy
11.4.3 Spain
11.4.4 Germany
11.4.5 France
11.4.6 Rest of Europe
11.5 Key Takeaways
12 ASIA PACIFIC MARKET ANALYSIS
12.1 APAC Market Revenue & Share Analysis, By Application
12.2 APAC Market Revenue & Share Analysis, By End User
12.3 APAC Market Revenue & Share Analysis, By Product
12.4 APAC Market Revenue & Share Analysis, By Country
12.4.1 China
12.4.2 Japan
12.4.3 India
12.4.4 South Korea
12.4.5 Rest of APAC
12.5 Key Takeaways
13 MIDDLE EAST & AFRICA MARKET
ANALYSIS
13.1 MEA Market Revenue & Share Analysis, By Application
13.2 MEA Market Revenue & Share Analysis, By End User
13.3 MEA Market Revenue & Share Analysis, By Product
13.4 MEA Market Revenue & Share Analysis, By Country
13.4.1 GCC
13.4.2 South Africa
13.4.3 Rest of MEA
13.5 Key Takeaways
14 SOUTH AMERICA MARKET ANALYSIS
14.1 SA Market Revenue & Share Analysis, By Application
14.2 SA Market Revenue & Share Analysis, By End User
14.3 SA Market Revenue & Share Analysis, By Product
14.4 SA Market Revenue & Share Analysis, By Country
14.4.1 Brazil
14.4.2 Argentina
14.4.3 Rest of SA
14.5 Key Takeaways
15 COMPETITIVE SCENARIO
15.1 Overview
15.2 Key Players Market Share Analysis
15.3 Recent Developments & Product Launches
15.4 Mergers & Acquisitions
15.5 Partnerships, Agreements & Collaborations
16 COMPANY PROFILES
16.1 Overview
16.2 Key players
16.2.1 QIAGEN (Germany)
16.2.1.1 Business Overview
16.2.1.2 Products Offered
16.2.1.3 Financial Insights
16.2.1.4 Strategic Developments
16.2.1.4.1 New Product Launches
16.2.1.4.2 Agreements & Collaborations
16.2.1.5 Business Aspects (NOISE Analysis)
16.2.1.5.1 Key Strengths
16.2.1.5.2 Opportunities
16.2.1.5.3 Weaknesses & Competitive Threats
16.2.1.5.4 Needs & Improvements
16.2.2 Thermo Fisher Scientific (US)
16.2.3 Sartorius AG (Germany)
16.2.4 Berthold Technologies GmbH & Co. KG
(India)
16.2.5 Promega Corp. (US)
16.2.6 Marker Gene Technologies, Inc. (US)
16.2.7 Merck KGaA (Germany)
16.2.8 F. Hoffmann-La Roche AG (Switzerland)
16.2.9 PerkinElmer Life Science (US)
16.2.10 Bio-Rad Laboratories (US)
17 DISCLAIMER
18 APPENDIX
